<?xml version="1.0" encoding="UTF-8"?>
<xs:schema version="1.0" targetNamespace="http://common.biosemantic.erasmusmc.org/" xmlns="http://common.biosemantic.erasmusmc.org/" xmlns:xml="http://www.w3.org/XML/1998/namespace" xmlns:xs="http://www.w3.org/2001/XMLSchema">

  <xs:annotation>
    <xs:documentation>Common data types v1.8</xs:documentation>
  </xs:annotation>

  <xs:import namespace="http://www.w3.org/XML/1998/namespace" schemaLocation="http://www.w3.org/2001/03/xml.xsd"/>

  <xs:complexType name="concept">
    <xs:sequence>
      <xs:element name="labels">
        <xs:annotation>
          <xs:documentation>The preferred or alternate names for this concept. Also referred to as "terms".</xs:documentation>
        </xs:annotation>
        <xs:complexType>
          <xs:sequence>
            <xs:element name="label" type="conceptLabel" maxOccurs="unbounded"/>
          </xs:sequence>
        </xs:complexType>
      </xs:element>
      <xs:element name="databaseIds" minOccurs="0">
        <xs:complexType>
          <xs:sequence>
            <xs:element name="databaseId" type="databaseId" maxOccurs="unbounded">
              <xs:annotation>
                <xs:documentation>The concept may occur in different databases with different identifiers and labels.</xs:documentation>
              </xs:annotation>
            </xs:element>
          </xs:sequence>
        </xs:complexType>
      </xs:element>
      <xs:element name="semanticTypes">
        <xs:complexType>
          <xs:sequence>
            <xs:element name="semanticType" type="semanticType" maxOccurs="unbounded">
              <xs:annotation>
                <xs:documentation>The Semantic group to which the concept belongs.</xs:documentation>
              </xs:annotation>
            </xs:element>
          </xs:sequence>
        </xs:complexType>
      </xs:element>
    </xs:sequence>
  </xs:complexType>

  <xs:complexType name="databaseId">
    <xs:annotation>
      <xs:documentation>The concept may occur in different databases with different identifiers and labels.</xs:documentation>
    </xs:annotation>
    <xs:sequence>
      <xs:element name="source" type="databaseSource" minOccurs="0" maxOccurs="1">
        <xs:annotation>
          <xs:documentation>The database name that contains the ID.</xs:documentation>
        </xs:annotation>
      </xs:element>
      <xs:element name="code" type="xs:string" minOccurs="0" maxOccurs="1">
        <xs:annotation>
          <xs:documentation>The database-specific ID for the concept.</xs:documentation>
        </xs:annotation>
      </xs:element>
      <xs:element name="name" type="xs:string" minOccurs="0" maxOccurs="1">
        <xs:annotation>
          <xs:documentation>The specific element name.</xs:documentation>
        </xs:annotation>
      </xs:element>
    </xs:sequence>
  </xs:complexType>

  <xs:simpleType name="databaseSource">
    <xs:restriction base="xs:string">
      <xs:enumeration value="AF">
        <xs:annotation>
          <xs:documentation>
            Affymetrix
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="AffinDB">
        <xs:annotation>
          <xs:documentation>
            The Affinity Database 'AffinDB' contains affinity data for protein-ligand complexes of the PDB.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ATC">
        <xs:annotation>
          <xs:documentation>
            Anatomical Therapeutic Chemical classification
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="BindingDB">
        <xs:annotation>
          <xs:documentation>
            The BindingDB is a public, web-accessible database of measured binding affinities for biomolecules, genetically or chemically modified biomolecules, and synthetic compounds.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="CAS">
        <xs:annotation>
          <xs:documentation>
            Chemical Abstracts Service registry number
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/portal/query.fcgi?CMD=search&amp;DB=pccompound&amp;term=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="CTD">
        <xs:annotation>
          <xs:documentation>
            &lt;a href="http://ctd.mdibl.org/"&gt;The comparative toxicogenomics database&lt;/a&gt;.
            &lt;br&gt;Added as to request from &lt;a href="mailto:abauer-mehren@imim.es"&gt;Anna Bauer-Mehren&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="CHEB">
        <xs:annotation>
          <xs:documentation>
            ChEBI
            &lt;br&gt;Link: "http://www.ebi.ac.uk/chebi/searchFreeText.do?searchString=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ChEMBL">
        <xs:annotation>
          <xs:documentation>
            &lt;a href="http://www.ebi.ac.uk/chembldb/index.php"&gt;ChEMBL&lt;/a&gt; is a database of ca. 500,000 bioactive compounds, their quantitative properties and bioactivities (binding constants, pharmacology and ADMET, etc). The data is abstracted and curated from the primary scientific literature and the data made available due to funding by the Wellcome Trust.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="CHID">
        <xs:annotation>
          <xs:documentation>
            ChemIDplus
            &lt;br&gt;Link: "http://chem.sis.nlm.nih.gov/chemidplus/ProxyServlet?objectHandle=DBMaint&amp;actionHandle=default&amp;nextPage=jsp/chemidlite/ResultScreen.jsp&amp;TXTSUPERLISTID=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="DAILYMED">
        <xs:annotation>
          <xs:documentation>
            DailyMed
            &lt;br&gt;Link: " http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?start=1&amp;ndc=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="DRUG">
        <xs:annotation>
          <xs:documentation>
            Drug Bank
            &lt;br&gt;Link: "http://www.drugbank.ca/drugs/" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ECO">
        <xs:annotation>
          <xs:documentation>
            EcoGene
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="EG">
        <xs:annotation>
          <xs:documentation>
            Entrez-Gene
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&amp;cmd=Retrieve&amp;dopt=full_report&amp;list_uids=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="EMBL">
        <xs:annotation>
          <xs:documentation>
            EMBL
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="EMC">
        <xs:annotation>
          <xs:documentation>
            ErasmusMC internal thesaurus ID. Should not be returned to external services unless is explicilty requested.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="EUADR_EVENT">
        <xs:annotation>
          <xs:documentation>
            Events identified in the EU-ADR project (events like "anaphylactic shock" (AS), "acute renal failure" (ARF), "acute myocardial infarction" (AMI) etc.)
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="FB">
        <xs:annotation>
          <xs:documentation>
            FlyBase
            &lt;br&gt;Link: "http://www.flybase.org/reports/" + ID + ".html"
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="GD">
        <xs:annotation>
          <xs:documentation>
            Human Genome Database
            &lt;br&gt;Link: "http://www.gdb.org/gdb-bin/genera/genera/hgd/DBObject/GDB:" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="GO">
        <xs:annotation>
          <xs:documentation>
            Gene Ontology
            &lt;br&gt;Link: "http://www.godatabase.org/cgi-bin/amigo/go.cgi?view=details&amp;search_constraint=terms&amp;depth=0&amp;query=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="GOID">
        <xs:annotation>
          <xs:documentation>
            Gene Ontology ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="GOTM">
        <xs:annotation>
          <xs:documentation>
            Gene Ontology Term
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="HG">
        <xs:annotation>
          <xs:documentation>
            HGNC
            &lt;br&gt;Link: "http://www.genenames.org/data/hgnc_data.php?hgnc_id=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="hGPCRlig">
        <xs:annotation>
          <xs:documentation>
            &lt;a href="http://cheminfo.u-strasbg.fr:8080/hGPCRlig/"&gt;hGPCRlig&lt;/a&gt; is a bank of 3-D human G-Protein Coupled Receptor models and their known ligands. To obtain "hits" that will be able to provide with a major probability "leads".
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="HMBD">
        <xs:annotation>
          <xs:documentation>
            Human Metabolome Database
            &lt;br&gt;Link: "http://hmp.biology.ualberta.ca/~knox/hmdb/metabolites/"+"ID"
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="HO">
        <xs:annotation>
          <xs:documentation>
            Homologene
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=homologene&amp;dopt=HomoloGene&amp;list_uids=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ICD9CM">
        <xs:annotation>
          <xs:documentation>
            ICD9-CM
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="INCH">
        <xs:annotation>
          <xs:documentation>
            IUPAC International Chemical Identifier
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/portal/query.fcgi?CMD=search&amp;DB=pccompound&amp;term=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ISBD">
        <xs:annotation>
          <xs:documentation>
            The International Standard Book Number (ISBN) is a unique numeric commercial book identifier based upon the 9-digit Standard Book Numbering (SBN) code.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="IUPHARdb">
        <xs:annotation>
          <xs:documentation>
            Database of Receptors and Ion Channels.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="KEGD">
        <xs:annotation>
          <xs:documentation>
            KEGD
            &lt;br&gt;Link: "http://www.genome.jp/dbget-bin/www_bget?drug:" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="KEGG">
        <xs:annotation>
          <xs:documentation>
            KEGG
            &lt;br&gt;Link: "http://www.genome.jp/dbget-bin/www_bget?cpd:" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="LL">
        <xs:annotation>
          <xs:documentation>
            Entrez-Gene
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&amp;cmd=Retrieve&amp;dopt=full_report&amp;list_uids=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MESH">
        <xs:annotation>
          <xs:documentation>
            Medical Subject Headings
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MGI">
        <xs:annotation>
          <xs:documentation>
            Mouse Genome Database
            &lt;br&gt;Link: "http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="LHGDN">
        <xs:annotation>
          <xs:documentation>
            Textmining resource with extraction of semantic biomedical relations from text of &lt;a href="http://www.biomedcentral.com/bmcbioinformatics/"&gt;BMC Bioinformatics.&lt;/a&gt; journal using conditional random fields.
            &lt;br&gt;Added as to request from &lt;a href="mailto:abauer-mehren@imim.es"&gt;Anna Bauer-Mehren&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MOAD">
        <xs:annotation>
          <xs:documentation>
            &lt;a href="http://www.bindingmoad.org/"&gt;Binding MOAD&lt;/a&gt;'s goal is to be the largest collection of well resolved protein crystal structures with clearly identified biologically relevant ligands annotated with experimentally determined binding data extracted from literature.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="NRacl">
        <xs:annotation>
          <xs:documentation>
            Annotated compound library directed to nuclear receptors as a means for integrating the chemical and biological data being generated within this family. All data incorporated in NRacl were collected from public sources of information, mainly reviews and medicinal chemistry journals of the last 10 years. For each chemical entity within NRacl, data are organized in four main sections, namely, structural, chemical, biological, and bibliographical.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="OLN">
        <xs:annotation>
          <xs:documentation>
            Ordered Locus Name
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="OM">
        <xs:annotation>
          <xs:documentation>
            OMIM
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="PDB">
        <xs:annotation>
          <xs:documentation>
            Protein Data Bank. The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="PDSP">
        <xs:annotation>
          <xs:documentation>
            This service provides screening of novel psychoactive compounds for pharmacological and functional activity at cloned human or rodent CNS receptors, channels, and transporters.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="PHARMGKB">
        <xs:annotation>
          <xs:documentation>
            &lt;a href="http://www.pharmgkb.org/"&gt;The Pharmacogenomics database&lt;/a&gt;.
            &lt;br&gt;Added as to request from &lt;a href="mailto:abauer-mehren@imim.es"&gt;Anna Bauer-Mehren&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="PMID">
        <xs:annotation>
          <xs:documentation>
            Pubmed
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&amp;cmd=Retrieve&amp;dopt=AbstractPlus&amp;list_uids=" + ID + "&amp;query_hl=1&amp;itool=pubmed_docsum"
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="PUBC">
        <xs:annotation>
          <xs:documentation>
            PubChem Compound
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/portal/query.fcgi?CMD=search&amp;DB=pccompound&amp;term=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="PUBS">
        <xs:annotation>
          <xs:documentation>
            PubChem Substance
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/portal/query.fcgi?CMD=search&amp;DB=pcsubstance&amp;term=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="RGD">
        <xs:annotation>
          <xs:documentation>
            Rat Genome Database
            &lt;br&gt;Link: "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=RGD:" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="RM">
        <xs:annotation>
          <xs:documentation>
            RatMap
            &lt;br&gt;Link: "http://www.ratmap.org/ShowSingleLocus.htm?accno=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="RQ">
        <xs:annotation>
          <xs:documentation>
            RefSeq
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="SGD">
        <xs:annotation>
          <xs:documentation>
            Saccharomyces Genome Database
            &lt;br&gt;Link: "http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="SMILE">
        <xs:annotation>
          <xs:documentation>
            The Simplified Molecular Input Line Entry Specification or SMILES is a specification for unambiguously describing the structure of chemical molecules using short ASCII strings.
            &lt;br&gt;Added as to request from &lt;a href="mailto:maria.carrascosa@upf.edu"&gt;Mari Carmen Carrascosa&lt;/a&gt;.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="SP">
        <xs:annotation>
          <xs:documentation>
            Swiss-Prot
            &lt;br&gt;Link: "http://ca.expasy.org/uniprot/" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="TAXON">
        <xs:annotation>
          <xs:documentation>
            Taxonomy ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="UG">
        <xs:annotation>
          <xs:documentation>
            UniGene
            &lt;br&gt;Link: "http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=" + ID.substring(0, 2) + "&amp;CID=" + ID.substring(3, ID.length())
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="UMLS">
        <xs:annotation>
          <xs:documentation>
            Unified Medical Language System
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="UP">
        <xs:annotation>
          <xs:documentation>
            UniProt
            &lt;br&gt;Link: "http://ca.expasy.org/uniprot/" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="WB">
        <xs:annotation>
          <xs:documentation>
            WormBase
            &lt;br&gt;Link: "http://www.wormbase.org/db/gene/gene?name=" + ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ZFIN">
        <xs:annotation>
          <xs:documentation>
            ZFIN
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>

      <xs:enumeration value="CWIKI">
        <xs:annotation>
          <xs:documentation>
            Conceptwiki &lt;br&gt;Link: "http://conceptwiki.org/index.php/Concept:" + Concept ID
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="SNOMEDCT">
        <xs:annotation>
          <xs:documentation>
            SNOMED CT (Systematized Nomenclature of Medicine -- Clinical Terms (updated) NOMEDCT_2009_07_31
            SNOMED Clinical Terms, 2009_07_31 International Health Terminology Standards Development Organization;SNOMED
            Clinical Terms;July 31, 2009;Chicago, IL;College of American Pathologists, 2009;http://ihtsdo.org;ENG
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="CRISP">
        <xs:annotation>
          <xs:documentation>
            Combinatorial Responses In Stress Pathways (CRISP) :
            http://www3.imperial.ac.uk/cisbic/research/crisp
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MEDLINE">
        <xs:annotation>
          <xs:documentation>
            MEDLINE, the U.S. National Library of Medicine's bibliographic database, consists of more than 11
            million articles from over 4,800 indexed titles.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="LNC">
        <xs:annotation>
          <xs:documentation>
            LNC (updated) LNC227 Logical Observation Identifier Names and Codes, 227 The Regenstrief
            Institute;Logical Observation Identifier Names and Codes (LOINC);Version 2.27;June 16, 2009;Indianapolis, IN;ENG
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="AOD">
        <xs:annotation>
          <xs:documentation>
            Alcohol and Other Drug Thesaurus, 2000 Alcohol and Other Drug Thesaurus: A Guide to Concepts and
            Terminology in Substance Abuse and Addiction. 3rd. ed. [4 Volumes.] Bethesda, MD: National Institute on Alcohol
            Abuse and Alcoholism (NIAAA) and Center for Substance Abuse Prevention (CSAP), 2000
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="CCPSS">
        <xs:annotation>
          <xs:documentation>
            Canonical Clinical Problem Statement System, 1999. Canonical Clincial Problem Statement System,
            Version 1.0 June 23, 1999. Contact: sbrown@vumclib.mc.vanderbilt.edu
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="CPT">
        <xs:annotation>
          <xs:documentation>
            Current Procedural Terminology, 2009. Current Procedural Terminology (CPT);American Medical
            Association;2009;Chicago, IL;ENG
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="FMA">
        <xs:annotation>
          <xs:documentation>
            FMA FMA2_0 Foundational Model of Anatomy Ontology, 2_0 Cornelius Rosse MD DSc, Jose L.V. Mejino
            Jr. MD;Foundational Model of Anatomy;2.0;Seattle, WA;ENG
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="HCPT">
        <xs:annotation>
          <xs:documentation>
            HCPT HCPT2009 HCPCS Version of Current Procedural Terminology (CPT), 2009 Version of Physicians.
            Current Procedural Terminology (CPT) included in the Healthcare Common Procedure Coding System (HCPCS) Centers for
            Medicare and Medicaid Services
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="HUGO">
        <xs:annotation>
          <xs:documentation>
            HUGO (updated) HUGO2009_04 HUGO Gene Nomenclature, 2009_04 Eyre TA, Ducluzeau F, Sneddon TP,
            Povey S, Bruford EA and Lush MJ;HGNC Database;The HUGO Gene Nomenclature Database;European Bioinformatics
            Institute Wellcome Trust Genome Campus;United Kingdom;ENG
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ICD10">
        <xs:annotation>
          <xs:documentation>
            ICD10 ICD10_1998 ICD10, 1998 International Statistical Classification of Diseases and Related
            Health Problems (ICD-10). 10th rev. Geneva (Switzerland): World Health Organization, 1998.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ICD10AM">
        <xs:annotation>
          <xs:documentation>
            ICD10AM ICD10AM_2000 International Statistical Classification of Diseases and Related
            HealthProblems, 10th Revision, Australian Modification, January 2000 ReleaseInternational Statistical
            Classification of Diseases and Related Health Problems, 10th Revision, Australian Modification; 2ndEdition,
            published January 2000.Developed and Maintained by the National Centre for Classification in Health,University of
            Sydney, Faculty of Health
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="ICD10PCS">
        <xs:annotation>
          <xs:documentation>
            ICD10PCS(updated) ICD10PCS_2009 ICD-10-PCS, 2009Centers for Medicare and
            MedicaidServices;ICD-10-PCS;Baltimore, MD;2009;http://www.cms.hhs.gov;ENG
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MDR">
        <xs:annotation>
          <xs:documentation>
            ICD10PCS(updated) ICD10PCS_2009 ICD-10-PCS, 2009Centers for Medicare and
            MedicaidServices;ICD-10-PCS;Baltimore, MD;2009;http://www.cms.hhs.gov;ENG
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MEDCIN">
        <xs:annotation>
          <xs:documentation>
            Medicomp Systems;MEDCIN;v.30;Medicomp Systems;2008;Chantilly, VA
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MMSL">
        <xs:annotation>
          <xs:documentation>
            Medisource Lexicon;August 01, 2009;Denver, CO;Multum Information Services, Inc.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MTHFDA">
        <xs:annotation>
          <xs:documentation>
            (updated) MTHFDA_2009_07_31 Metathesaurus FDA National Drug Code Directory, 2009_07_31
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="MTHICD9">
        <xs:annotation>
          <xs:documentation>
            Metathesaurus additional entry terms for ICD-9-CM [computer file]: International Classification
            of Diseases, Ninth Revision, Clinical Modification;National Library of Medicine;October 1, 2009;Bethesda, MD
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="NCBI">
        <xs:annotation>
          <xs:documentation>
            U.S. Department of Health and Human Services;NCBI Taxonomy;National Institutes of Health,
            National Library of Medicine, National Center for Biotechnology Information;April 13, 2009;Bethesda, MD
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="NCI">
        <xs:annotation>
          <xs:documentation>
            National Cancer Institute, National Institutes of Health;Sherri de Coronado;NCI
            Thesaurus;National Cancer Institute;OWL version, April 2009;Bethesda, MD
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="NDDF">
        <xs:annotation>
          <xs:documentation>
            NDDF_2009_08_07 National Drug Data File Plus Source Vocabulary, 2009_08_07. National Drug Data
            File Plus Source Vocabulary 2008;August 07, 2009;San Bruno, CA;First DataBank
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="NDFRT">
        <xs:annotation>
          <xs:documentation>
            NDFRT NDFRT_2008_03_11 National Drug File - Reference Terminology Public Inferred Edition,
            2008_03_11
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="PDQ">
        <xs:annotation>
          <xs:documentation>
            PDQ PDQ2007_02 Physician Data Query, 2007_02
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="RCD">
        <xs:annotation>
          <xs:documentation>
            RCD99 Clinical Terms Version 3 (CTV3) (Read Codes), 1999. Clinical Terms Version 3 (CTV3) (Read
            Codes) (Q199): National Health Service National Coding and Classification Centre; March, 1999.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="RCDAE">
        <xs:annotation>
          <xs:documentation>
            RCDAE_1999 Read thesaurus, American English Equivalents, 1999. American English equivalent of the
            Clinical Terms Version 3 (Q1, 1999), produced by NLM. Bethesda (MD): National Library ofMedicine, UMLS
            project,1999.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="RCDSY">
        <xs:annotation>
          <xs:documentation>
            RCDSY RCDSY_1999 Read thesaurus, Synthesized Terms, 1999. Synthesized Read terms (without initial
            bracketed letters) of the Clinical Terms Version 3 (Q1, 1999), produced by NLM. Bethesda (MD): National Library of
            Medicine, UMLS project,1999.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="RXNORM">
        <xs:annotation>
          <xs:documentation>
            RXNORM (updated) RXNORM_09AA_090908F RxNorm Vocabulary, 09AA_090908F RxNorm;META2009AA Full
            Update 2009_09_08;Bethesda, MD;National Library of Medicine
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>

      <xs:enumeration value="SNM">
        <xs:annotation>
          <xs:documentation>
            SNOMED-2, 2. Cote, Roger A., editor. Systematized Nomenclature of Medicine. 2nd ed. Skokie (IL):
            College of American Pathologists, 1979. SNOMED update, 1982. Skokie (IL): College of American Pathologists, 1982.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>

      <xs:enumeration value="SNMI">
        <xs:annotation>
          <xs:documentation>
            SNMI SNMI98 SNOMED International, 1998 Cote, Roger A., editor. Systematized Nomenclature of Human
            and Veterinary Medicine: SNOMED International. Northfield (IL): College of American Pathologists; Schaumburg (IL)
            American Veterinary Medical Association, Version 3.5, 1998.
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>

      <xs:enumeration value="UMD">
        <xs:annotation>
          <xs:documentation>
            UMD2009 UMDNS: product category thesaurus, 2009 The Universal Medical Device Nomenclature
            System;ECRI;Plymouth Meeting;2009
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="UWDA">
        <xs:annotation>
          <xs:documentation>
            UWDA173 University of Washington Digital Anatomist, 1.7.3 University of Washington Digital
            Anatomist, (UWDA). Seattle
            (WA): University of Washinton, Version 1.7.3, March, 2003. Jose Mejino, M.D.; email:
            onard@biostr.washington.edu
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>
      <xs:enumeration value="VANDF">
        <xs:annotation>
          <xs:documentation>
            (updated) VANDF_2009_07_29 Veterans Health Administration National Drug File, 2009_07_29 Veterans
            Health Administration National Drug File;July 29, 2009;Washington, DC;U.S. Department of Veterans Affairs
          </xs:documentation>
        </xs:annotation>
      </xs:enumeration>

      <!-- Below sources were added as to request of Paul Avillach <paul.avillach@isped.u-bordeaux2.fr> -->
      <xs:enumeration value="PUBMED_JOURNAL_ARTICLE"/>
      <xs:enumeration value="PUBMED_CASE_REPORTS"/>
      <xs:enumeration value="PUBMED_CLASSICAL_ARTICLE"/>
      <xs:enumeration value="PUBMED_CLINICAL_CONFERENCE"/>
      <xs:enumeration value="PUBMED_CLINICAL_TRIAL"/>
      <xs:enumeration value="PUBMED_CLINICAL_TRIAL_PHASE_I"/>
      <xs:enumeration value="PUBMED_CLINICAL_TRIAL_PHASE_II"/>
      <xs:enumeration value="PUBMED_CLINICAL_TRIAL_PHASE_III"/>
      <xs:enumeration value="PUBMED_CLINICAL_TRIAL_PHASE_IV"/>
      <xs:enumeration value="PUBMED_COMPARATIVE_STUDY"/>
      <xs:enumeration value="PUBMED_CONGRESSES"/>
      <xs:enumeration value="PUBMED_CONSENSUS_DEVELOPMENT_CONFERENCE"/>
      <xs:enumeration value="PUBMED_CONSENSUS_DEVELOPMENT_CONFERENCE_NIH"/>
      <xs:enumeration value="PUBMED_CONTROLLED_CLINICAL_TRIAL"/>
      <xs:enumeration value="PUBMED_CORRECTED_AND_REPUBLISHED_ARTICLE"/>
      <xs:enumeration value="PUBMED_EVALUATION_STUDIES"/>
      <xs:enumeration value="PUBMED_GUIDELINE"/>
      <xs:enumeration value="PUBMED_LEGAL_CASES"/>
      <xs:enumeration value="PUBMED_LETTER"/>
      <xs:enumeration value="PUBMED_META-ANALYSIS"/>
      <xs:enumeration value="PUBMED_MULTICENTER_STUDY"/>
      <xs:enumeration value="PUBMED_NEWSPAPER_ARTICLE"/>
      <xs:enumeration value="PUBMED_OVERALL"/>
      <xs:enumeration value="PUBMED_PORTRAITS"/>
      <xs:enumeration value="PUBMED_PRACTICE_GUIDELINE"/>
      <xs:enumeration value="PUBMED_RANDOMIZED_CONTROLLED_TRIAL"/>
      <xs:enumeration value="PUBMED_REVIEW"/>
      <xs:enumeration value="PUBMED_TECHNICAL_REPORT"/>
      <xs:enumeration value="PUBMED_TWIN_STUDY"/>
      <xs:enumeration value="PUBMED_VALIDATION_STUDIES"/>
    </xs:restriction>
  </xs:simpleType>

  <xs:complexType name="label">
    <xs:simpleContent>
      <xs:extension base="xs:string">
        <xs:annotation>
          <xs:documentation>The language-dependent text.</xs:documentation>
        </xs:annotation>
        <xs:attribute ref="xml:lang" use="required">
          <xs:annotation>
            <xs:documentation>The language ISO code as specified in RFC 3066.</xs:documentation>
          </xs:annotation>
        </xs:attribute>
      </xs:extension>
    </xs:simpleContent>
  </xs:complexType>

  <xs:complexType name="conceptLabel">
    <xs:sequence>
      <xs:element name="text" type="xs:string">
        <xs:annotation>
          <xs:documentation>The language-dependent text.</xs:documentation>
        </xs:annotation>
      </xs:element>
    </xs:sequence>
    <xs:attribute ref="xml:lang" use="required">
      <xs:annotation>
        <xs:documentation>The language ISO code as specified in RFC 3066.</xs:documentation>
      </xs:annotation>
    </xs:attribute>
    <xs:attribute name="type" type="labelType" use="required"/>
  </xs:complexType>

  <xs:simpleType name="labelType">
    <xs:annotation>
      <xs:documentation>This types where chosen as in SKOS (http://www.w3.org/TR/2009/REC-skos-reference-20090818/#labels)</xs:documentation>
    </xs:annotation>
    <xs:restriction base="xs:string">
      <xs:enumeration value="PREFERRED"/>
      <xs:enumeration value="ALTERNATE"/>
      <xs:enumeration value="HIDDEN"/>
    </xs:restriction>
  </xs:simpleType>

  <xs:complexType name="semanticType">
    <xs:sequence>
      <xs:element name="id" type="xs:string">
        <xs:annotation>
          <xs:documentation>Semantic type is uniquely identified by ID.</xs:documentation>
        </xs:annotation>
      </xs:element>
    </xs:sequence>
  </xs:complexType>
</xs:schema>